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N-Formyl Saxagliptin

Synonyms: N-((S)-2-((1S,3S,5S)-3-Cyano-2-azabicyclo[3.1.0]hexan-2-yl)-1-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)-2-oxoethyl)formamide
Cat. No.: S12026 CAS No.: N.A.
MDL.: Formula: C19H25N3O3
F.W.343.42 Purity: 99%
Storage:
 
Size/Unit Price Qty Availability Price Total
5mg $175.00 Enter qty and click checkbox $175.00
Catalog Number: S12026   CAS No.: N.A.
MDL: Formula: C19H25N3O3
F.W.: 343.42 Purity: 99%
Package: Unit: mg
Appearance: M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Stability:
Storage: Category: Reference Standard
Reference: Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008)
Application: N-Formyl Saxagliptin is an impurity of Saxagliptin, a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
Category: Amines, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals