N-Formyl Saxagliptin |
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Synonyms: N-((S)-2-((1S,3S,5S)-3-Cyano-2-azabicyclo[3.1.0]hexan-2-yl)-1-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)-2-oxoethyl)formamide | |
Cat. No.: S12026 | CAS No.: N.A. |
MDL.: | Formula: C19H25N3O3 |
F.W.343.42 | Purity: 99% |
Storage: | |
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Catalog Number: | S12026 | CAS No.: | N.A. | |
MDL: | Formula: | C19H25N3O3 | ||
F.W.: | 343.42 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008) | |||
Application: | N-Formyl Saxagliptin is an impurity of Saxagliptin, a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing. | |||
Category: | Amines, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals |