3-Descarbonitrile 3-Acetamido Saxagliptin |
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| Synonyms: (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo [3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carboxamide | |
| Cat. No.: S12027 | CAS No.: 1496712-39-0 |
| MDL.: | Formula: C18H27N3O3 |
| F.W.333.43 | Purity: 99% |
| Storage: | |
| Size/Unit | Price | Qty | Availability | Price Total |
|---|---|---|---|---|
| 5mg | $175.00 | Enter qty and click checkbox |
 
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$175.00 |
| Catalog Number： | S12027 | CAS No.: | 1496712-39-0 | |
| MDL: | Formula: | C18H27N3O3 | ||
| F.W.: | 333.43 | Purity: | 99% | |
| Package: | Unit: | mg | ||
| Appearance: | M.P.: | |||
| B.P.: | Density: | |||
| Optical Rotation: | Refractive Index: | |||
| Solubility: | Stability: | |||
| Storage: | Category: | Reference Standard | ||
| Reference: | Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008) | |||
| Application: | 3-Descarbonitrile 3-Acetamido Saxagliptin is a Saxagliptin impurity, a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing. | |||
| Category: | Amines, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals | |||