Saxagliptin Impurity A |
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| Synonyms: Boc-3-hydroxy-1-adamantyl-L-glycine; (2R)-2-((tert-Butoxycarbonyl)amino)-2-(3-hydroxyadamantan-1-yl)acetic Acid; (aR)-a-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-hydroxy-tricyclo[3.3.1.13,7]decane-1-acetic Acid | |
| Cat. No.: S12029 | CAS No.: 1334321-39-9 |
| MDL.: | Formula: C17H27NO5 |
| F.W.325.4 | Purity: 99% |
| Storage: | |
| Size/Unit | Price | Qty | Availability | Price Total |
|---|---|---|---|---|
| 10mg | $175.00 | Enter qty and click checkbox |
 
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$175.00 |
| Catalog Number： | S12029 | CAS No.: | 1334321-39-9 | |
| MDL: | Formula: | C17H27NO5 | ||
| F.W.: | 325.4 | Purity: | 99% | |
| Package: | Unit: | mg | ||
| Appearance: | M.P.: | |||
| B.P.: | Density: | |||
| Optical Rotation: | Refractive Index: | |||
| Solubility: | Stability: | |||
| Storage: | Category: | Reference Standard | ||
| Reference: | Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008), | |||
| Application: | Boc-3-hydroxy-1-adamantyl-L-glycine is an impurity of Saxagliptin, which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing. | |||
| Category: | Amino Acids & Derivatives, Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals | |||