Saxagliptin Metabolite B |
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Synonyms: Saxagliptin Cyclic Amide; (1aS,4S,6aR,7aS)-Hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-1H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-3,6-dione | |
Cat. No.: S12036 | CAS No.: 1350800-77-9 |
MDL.: | Formula: C18H24N2O3 |
F.W.316.39 | Purity: 99% |
Storage: | |
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Catalog Number: | S12036 | CAS No.: | 1350800-77-9 | |
MDL: | Formula: | C18H24N2O3 | ||
F.W.: | 316.39 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Jones, G.S., et al.: J. Org. Chem., 76, 10332 (2011); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008) | |||
Application: | Saxagliptin Cyclic Amide is a degradation product of Saxagliptin; a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes. | |||
Category: | Chiral Reagents, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals |