Saxagliptin Metabolite C |
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Synonyms: (1aS,4S,6aR,7aS)-6-Amino-4-(3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)-1,1a,4,6a,7,7a-hexahydro-3H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one ;(1aS,4S,6aR,7aS)-4-((1r,3R,5S,7S)-3,5-Dihydroxyadamantan-1-yl)-6-iminohexahydro-1H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3(1aH)-one | |
Cat. No.: S12037 | CAS No.: 1429782-93-3 |
MDL.: | Formula: C18H25N3O2 |
F.W.331.41 | Purity: 99% |
Storage: | |
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Catalog Number: | S12037 | CAS No.: | 1429782-93-3 | |
MDL: | Formula: | C18H25N3O2 | ||
F.W.: | 331.41 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008); Su, H., et al.: Drug Metab. Dispos., 40, 1345 (2012) | |||
Application: | (1aS,4S,6aR,7aS)-6-Amino-4-(3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)-1,1a,4,6a,7,7a-hexahydro-3H-cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one is a metabolite of Saxagliptin; a potent dipeptidyl peptidase-4 inhibitor approved for the treatment of type 2 diabetes mellitus. | |||
Category: | Amines, Chiral Reagents, Miscellaneous Reagents |