Saxagliptin-15N,D2 Hydrochloride |
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Synonyms: (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile-15N,D2 Hydrochloride; BMS 477118-15N,D2 Hydrochloride; BMS 477118-11-15N,D2 Hydrochloride; Onglyza-15N,D2 Hydrochloride; | |
Cat. No.: S12066 | CAS No.: 1309934-06-2/ 361442-04-8(unlabelled) |
MDL.: | Formula: C18H24D2ClN2¹5NO2 |
F.W.354.88 | Purity: 99% |
Storage: | |
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Catalog Number: | S12066 | CAS No.: | 1309934-06-2/ 361442-04-8(unlabelled) | |
MDL: | Formula: | C18H24D2ClN2¹5NO2 | ||
F.W.: | 354.88 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Feng, J., et al.: J. Med. Chem., 50, 2297 (2007),Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008), | |||
Application: | Isotope labelled Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing. | |||
Category: | Amines, Chiral Reagents, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals |