Home> Products

Saxagliptin-15N,D2 Hydrochloride

Synonyms: (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile-15N,D2 Hydrochloride; BMS 477118-15N,D2 Hydrochloride; BMS 477118-11-15N,D2 Hydrochloride; Onglyza-15N,D2 Hydrochloride;
Cat. No.: S12066 CAS No.: 1309934-06-2/ 361442-04-8(unlabelled)
MDL.: Formula: C18H24D2ClN2¹5NO2
F.W.354.88 Purity: 99%
Storage:
 
Size/Unit Price Qty Availability Price Total
0.5mg $275.00 Enter qty and click checkbox $275.00
Catalog Number: S12066   CAS No.: 1309934-06-2/ 361442-04-8(unlabelled)
MDL: Formula: C18H24D2ClN2¹5NO2
F.W.: 354.88 Purity: 99%
Package: Unit: mg
Appearance: M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Stability:
Storage: Category: Reference Standard
Reference: Feng, J., et al.: J. Med. Chem., 50, 2297 (2007),Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),
Application: Isotope labelled Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
Category: Amines, Chiral Reagents, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals