Ribociclib (LEE011) |
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Synonyms: 7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; LEE-011, LEE 011 | |
Cat. No.: R20500 | CAS No.: 1256963-02-6 |
MDL.: | Formula: C23H30N8O |
F.W.434.45 | Purity: 99% |
Storage: | |
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Catalog Number: | R20500 | CAS No.: | 1256963-02-6 | |
MDL: | Formula: | C23H30N8O | ||
F.W.: | 434.45 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO | Stability: | ||
Storage: | Category: | Reference Standard | ||
Application: | LEE011 is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with potential antineoplastic activity. |