BGJ398 |
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Synonyms: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea ; BGJ-398 | |
Cat. No.: B98000 | CAS No.: 872511-34-7 |
MDL.: | Formula: C26H31Cl2N7O3 |
F.W.560.48 | Purity: 99% |
Storage: | |
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Catalog Number: | B98000 | CAS No.: | 872511-34-7 | |
MDL: | Formula: | C26H31Cl2N7O3 | ||
F.W.: | 560.48 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO | Stability: | ||
Storage: | Category: | Reference Standard | ||
Application: | BGJ398 is a potent and selective inhibitor with potential antiangiogenic and antineoplastic activities of fibroblast growth factor receptor (FGFR) tyrosine kinases 1, 2, 3 and 4 (with IC50 values of 0.9, 1.4, 1.0 and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4 respectively). |