Candesartan Intermediate C |
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Synonyms: 2-(2-Methoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole; 4,5-Dihydro-2-(2-methoxyphenyl)-4,4-dimethyl-oxazole; 2-(2-Methoxyphenyl)-4,4-dimethyl-2-oxazoline; 2-(2-Methoxyphenyl)-4,4-dimethyloxazoline; 4,4-Dimethyl-2-(2-methoxyphenyl)oxazoline; NSC 333420 | |
Cat. No.: C16042 | CAS No.: 57598-33-1 |
MDL.: | Formula: C12H15NO2 |
F.W.205.25 | Purity: 99% |
Storage: | |
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Catalog Number: | C16042 | CAS No.: | 57598-33-1 | |
MDL: | Formula: | C12H15NO2 | ||
F.W.: | 205.25 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Kaur, N., et al.: Bioorg. Med. Chem., 16, 10210 (2008); Funao, K., et al.: Mol. Med. Rep., 2, 193 (2009); Yoshikawa, M., et al.: J. Cardiovas. Pharmacol., 53, 179 (2009); Palaniyappan, A., et al.: Mol. Cell. Biochem., 321, 9 (2009) | |||
Application: | 2-(2-Methoxyphenyl)-4,4-dimethyl-4,5-dihydrooxazole is an intermediate in the synthesis of Candesartan-d4, the labeled analogue of Candesartan, an angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive. | |||
Category: | Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals |