Candesartan Intermediate F |
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Synonyms: 2-Oxo-2-(1-phenyl-1H-pyrazol-4-yl)acetic Acid;a-Oxo-1-phenyl-1H-pyrazole-4-acetic Acid | |
Cat. No.: C16045 | CAS No.: 1152495-65-2 |
MDL.: | Formula: C11H8N2O3 |
F.W.216.19 | Purity: 99% |
Storage: | |
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Catalog Number: | C16045 | CAS No.: | 1152495-65-2 | |
MDL: | Formula: | C11H8N2O3 | ||
F.W.: | 216.19 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Seki, M. et. al: ACS Catalysis, 4, 4047 (2014); Shibouta, Y., et al.: J. Pharmacol. Exp. Ther., 266, 114 (1993; Ogihara, T., et al.: Clin. Ther., 16, 74 (1994) | |||
Application: | 2-Oxo-2-(1-phenyl-1H-pyrazol-4-yl)acetic Acid is a derivative of N-Phenylpyrazole, a reactant in the synthesis of candesartan cilexetil, an ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive. | |||
Category: | Aromatics, Heterocycles, Miscellaneous Reagents |