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Candesartan Intermediate G

Synonyms: 1-Phenyl-pyrazole 4-pyruvic Acid; 2-Oxo-3-(1-phenyl-1H-pyrazol-4-yl)propanoic Acid; a-Oxo-1-phenyl-1H-pyrazole-4-propanoic Acid
Cat. No.: C16046 CAS No.: 1052567-31-3
MDL.: Formula: C12H10N2O3
F.W.230.22 Purity: 99%
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10mg $150.00 Enter qty and click checkbox $150.00
Catalog Number: C16046   CAS No.: 1052567-31-3
MDL: Formula: C12H10N2O3
F.W.: 230.22 Purity: 99%
Package: Unit: mg
Appearance: M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Stability:
Storage: Category: Reference Standard
Reference: Seki, M. et. al: ACS Catalysis, 4, 4047 (2014); Shibouta, Y., et al.: J. Pharmacol. Exp. Ther., 266, 114 (1993; Ogihara, T., et al.: Clin. Ther., 16, 74 (1994)
Application: 1-Phenyl-pyrazole 4-pyruvic Acid is a derivative of N-Phenylpyrazole, a reactant in the synthesis of candesartan cilexetil, an ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive.
Category: Aromatics, Heterocycles, Miscellaneous Reagents