| Catalog Number： |
A86001 |
|
CAS No.: |
885126-40-9 |
| MDL: |
|
|
Formula: |
C22H18N4OS |
| F.W.: |
386.47 |
|
Purity: |
99％ |
| Package: |
|
|
Unit: |
mg |
| Appearance: |
Pale Yellow to Light Yellow Solid |
|
M.P.: |
174 - 177°C |
| B.P.: |
|
|
Density: |
|
| Optical Rotation: |
|
|
Refractive Index: |
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| Solubility: |
DMSO (Slightly, Heated), Methanol (Slightly, Heated) Chloroform (Slightly), DMSO (Slightly) |
|
Stability: |
|
| Storage: |
-20°C, Inert atmosphere |
|
Category: |
Reference Standard |
| Reference: |
Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003), |
| Application: |
N-Methyl-2-[[3-[(1Z)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide is an impurity of Axitinib, a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. |
| Category: |
Aromatics, Impurities & Metabolites, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors, |
