Catalog Number: |
A86048 |
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CAS No.: |
886230-77-9 |
MDL: |
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Formula: |
C19H18IN3O |
F.W.: |
431.27 |
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Purity: |
99% |
Package: |
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Unit: |
mg |
Appearance: |
White to Light Yellow Solid |
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M.P.: |
156-159°C |
B.P.: |
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Density: |
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Optical Rotation: |
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Refractive Index: |
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Solubility: |
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
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Stability: |
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Storage: |
Amber Vial, Refrigerator |
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Category: |
Reference Standard |
Reference: |
Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003), |
Application: |
(E)-6-Iodo-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole is an intermediate used to prepare Axitinib as a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. |
Category: |
Aromatics, Inhibitors, Intermediates, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors, |