Azathioprine Impurity D |
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Synonyms: 1-methyl-4-nitro-1H-imidazole-5-thiol;1-Methyl-4-nitro-1H-imidazole-5-thiol; 1-Methyl-4-nitro-imidazole-5-thiol; 5-Mercapto-1-methyl-4-nitroimidazole ; EP Azathioprine Impurity D | |
Cat. No.: A86504 | CAS No.: 6339-54-4 |
MDL.: | Formula: C4H5N3O2S |
F.W.159.17 | Purity: 99% |
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere | |
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Catalog Number: | A86504 | CAS No.: | 6339-54-4 | |
MDL: | Formula: | C4H5N3O2S | ||
F.W.: | 159.17 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | Orange Solid | M.P.: | 38-42°C | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO (Slightly), Methanol (Slightly) | Stability: | ||
Storage: | Hygroscopic, -20°C Freezer, Under inert atmosphere | Category: | Reference Standard | |
Reference: | Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979); Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979); Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987); Sandborn, W.J., et al.: : Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998) | |||
Application: | 1-Methyl-4-nitro-5-thioimidazole is a metabolite of Azathioprine ; an immunosuppressive antimetabolite which is also active as a disease modifying antirheumatic drug (DMARD). Azathioprine is a purine analog with immunosuppressive effects. | |||
Category: | Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals |