Azathioprine Impurity E |
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Synonyms: 1-Methyl-4-nitro-1H-imidazol-5-ol; 1-Methyl-4-nitro-5-hydroxyimidazole; 5-Hydroxy-1-methyl-4-nitroimidazole;;EP Azathioprine Impurity E | |
Cat. No.: A86505 | CAS No.: 73703-74-9 |
MDL.: | Formula: C4H5N3O3 |
F.W.143.1 | Purity: 99% |
Storage: Refrigerator | |
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Catalog Number: | A86505 | CAS No.: | 73703-74-9 | |
MDL: | Formula: | C4H5N3O3 | ||
F.W.: | 143.1 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | No Data Available | M.P.: | No Data Available | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | No Data Available | Stability: | ||
Storage: | Refrigerator | Category: | Reference Standard | |
Reference: | Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979); Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979); Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987); Sandborn, W.J., et al.: Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998) | |||
Application: | 5-Hydroxy-1-methyl-4-nitroimidazole is a degradation product of Azathioprine ; an immunosuppressive antimetabolite that is also active as a disease modifying antirheumatic drug (DMARD). | |||
Category: | Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals |