Zonisamide Intermediate E-d4 |
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Synonyms: 3-(Bromomethyl)-1,2-benzisoxazole-d4;3-(Bromomethyl)-1,2-benzisoxazole-d4; 3-Bromomethylbenzisoxazole-d4; 3-Bromomethylbenzo[d]isoxazole-d4 | |
Cat. No.: Z78062 | CAS No.: Unlableed: 37924-85-9 |
MDL.: | Formula: C8H2D4BrNO |
F.W.216.07 | Purity: 99% |
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Catalog Number: | Z78062 | CAS No.: | Unlableed: 37924-85-9 | |
MDL: | Formula: | C8H2D4BrNO | ||
F.W.: | 216.07 | Purity: | 99% | |
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Optical Rotation: | Refractive Index: | |||
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Storage: | Category: | Reference Standard | ||
Reference: | Masuda, Y., et al.: Arzneim.-Forsch., 30, 477 (1980), Hammond, E.J., et al.: Gen. Pharmacol., 18, 303 (1987), Schmidt, D., et al.: Epilepsy Res., 15, 67 (1993), Sorkin, E.M., et al.: Drugs, 45, 760 (1993), | |||
Application: | 3-(Bromomethyl)-1,2-benzisoxazole-d4 is an intermediate in the synthesis of Zonisamide-d4; Labelled sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Anticonvulsant. | |||
Category: | Isotope Labelled Compounds,Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds |