Axitinib Intermediate G |
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Synonyms: Des-6-((2-(Methylcarbamoyl)phenyl)thio) Axitinib N-Oxide;(E)-2-(2-(6-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)vinyl)pyridine 1-Oxide. | |
Cat. No.: A86046 | CAS No.: N.A. |
MDL.: | Formula: C19H18IN3O2 |
F.W.447.28 | Purity: 99 |
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Catalog Number: | A86046 | CAS No.: | N.A. | |
MDL: | Formula: | C19H18IN3O2 | ||
F.W.: | 447.28 | Purity: | 99 | |
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Storage: | Category: | Reference Standard | ||
Reference: | Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003), | |||
Application: | Des-6-((2-(Methylcarbamoyl)phenyl)thio) Axitinib N-Oxide is an intermediate in the synthesis of Axitinib N-Oxide, a metabolite of Axitinib which is is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. | |||
Category: | Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors, |