Axitinib Intermediate F |
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Synonyms: Axitinib N-Oxide Tetrahydropyranyl Ether;(E)-2-(2-(6-((2-(methylcarbamoyl)phenyl)thio)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)vinyl)pyridine 1-oxide. | |
Cat. No.: A86045 | CAS No.: 2120337-09-7 |
MDL.: | Formula: C27H26N4O3S |
F.W.486.59 | Purity: 99 |
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Catalog Number: | A86045 | CAS No.: | 2120337-09-7 | |
MDL: | Formula: | C27H26N4O3S | ||
F.W.: | 486.59 | Purity: | 99 | |
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Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Stability: | |||
Storage: | Category: | Reference Standard | ||
Reference: | Wasser, K., et al.: Eur. Radiol., 13, 80 (2003), Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002), Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003), | |||
Application: | Axitinib N-Oxide Tetrahydropyranyl Ether is an intermediate in the synthesis of Axitinib N-Oxide, a metabolite of Axitinib which is is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy. | |||
Category: | Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors, |