Paliperidone S-Isomer |
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Synonyms: (S)-9-Hydroxy Risperidone;Paliperidone S-Isomer; (9S)-3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; (-)-9-Hydroxyrisperidone; 9-(S)-Paliperidone | |
Cat. No.: P09002 | CAS No.: 147663-01-2 |
MDL.: | Formula: C23H27FN4O3 |
F.W.426.48 | Purity: 99% |
Storage: -20°C | |
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Catalog Number: | P09002 | CAS No.: | 147663-01-2 | |
MDL: | Formula: | C23H27FN4O3 | ||
F.W.: | 426.48 | Purity: | 99% | |
Package: | Unit: | |||
Appearance: | White to Off-White Solid | M.P.: | >146°C (dec.) | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) | Stability: | ||
Storage: | -20°C | Category: | Reference Standard | |
Reference: | Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998),Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001),Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005), | |||
Application: | (S)-9-Hydroxy Risperidoneis the S-enantiomer metabolite of Risperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. | |||
Category: | Amines, Aromatics, Chiral Regents,Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals |