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Paliperidone Intermediate H

Synonyms: 3-(2-Chloroethyl)-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione;Paliperidone Impurity 5
Cat. No.: P09068 CAS No.: 1138463-56-5
MDL.: Formula: C11H13ClN2O2
F.W.240.69 Purity: 99%
Storage: Refrigerator
 
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Catalog Number: P09068   CAS No.: 1138463-56-5
MDL: Formula: C11H13ClN2O2
F.W.: 240.69 Purity: 99%
Package: Unit:
Appearance: M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Chloroform, Methanol Stability:
Storage: Refrigerator Category: Reference Standard
Reference: Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),
Application: 3-(2-Chloroethyl)-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione is an intermediate in the synthesis of Paliperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.
Category: Amine,Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals