Paliperidone Intermediate H |
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Synonyms: 3-(2-Chloroethyl)-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione;Paliperidone Impurity 5 | |
Cat. No.: P09068 | CAS No.: 1138463-56-5 |
MDL.: | Formula: C11H13ClN2O2 |
F.W.240.69 | Purity: 99% |
Storage: Refrigerator | |
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Catalog Number: | P09068 | CAS No.: | 1138463-56-5 | |
MDL: | Formula: | C11H13ClN2O2 | ||
F.W.: | 240.69 | Purity: | 99% | |
Package: | Unit: | |||
Appearance: | M.P.: | |||
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | Chloroform, Methanol | Stability: | ||
Storage: | Refrigerator | Category: | Reference Standard | |
Reference: | Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005), | |||
Application: | 3-(2-Chloroethyl)-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione is an intermediate in the synthesis of Paliperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. | |||
Category: | Amine,Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals |