Paliperidone Intermediate I |
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Synonyms: 3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7-dihydro-4H-pyrido[1,2-a]pyrimidin-4-one;Paliperidone Impurity 14 | |
Cat. No.: P09069 | CAS No.: N.A. |
MDL.: | Formula: C11H13ClN2O2 |
F.W.240.69 | Purity: 99% |
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Catalog Number: | P09069 | CAS No.: | N.A. | |
MDL: | Formula: | C11H13ClN2O2 | ||
F.W.: | 240.69 | Purity: | 99% | |
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Storage: | Category: | Reference Standard | ||
Reference: | Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005), | |||
Application: | 3-(2-Chloroethyl)-9-hydroxy-2-methyl-6,7-dihydro-4H-pyrido[1,2-a]pyrimidin-4-one is an intermediate in the synthesis of Paliperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. | |||
Category: | Amine,Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals |