Agomelatine |
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| Synonyms: N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide;N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide;N-[2-(7-Methoxy-1-naphthalenyl)ethyl]acetamide; N-[2-(7-Methoxy-1-naphthyl) ethyl]acetamide; S 20098; Valdoxan | |
| Cat. No.: A11000 | CAS No.: 138112-76-2 |
| MDL.: | Formula: C15H17NO2 |
| F.W.243.31 | Purity: 99％ |
| Storage: at-20°C Freezer | |
| Size/Unit | Price | Qty | Availability | Price Total |
|---|---|---|---|---|
| 1mg | POA | Enter qty and click checkbox |
| Catalog Number： | A11000 | CAS No.: | 138112-76-2 | |
| MDL: | Formula: | C15H17NO2 | ||
| F.W.: | 243.31 | Purity: | 99％ | |
| Package: | Unit: | mg | ||
| Appearance: | White solid | M.P.: | 107-109°C | |
| B.P.: | Density: | |||
| Optical Rotation: | Refractive Index: | |||
| Solubility: | Chloroform, Methanol | Stability: | ||
| Storage: | at-20°C Freezer | Category: | Reference Standard | |
| Reference: | Yous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003), | |||
| Application: | Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydr | |||
| Category: | Aromatics, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals | |||