Agomelatine-d4 |
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| Synonyms: Agomelatine-d4;N-[2-(7-Methoxy-1-naphthalenyl)ethyl-d4]acetamide; N-[2-(7-Methoxy-1-naphthyl) ethyl]acetamide-d4; S 20098-d4; Valdoxan-d4; | |
| Cat. No.: A11030 | CAS No.: unlabelled: 138112-76-2 |
| MDL.: | Formula: C15H13D4NO2 |
| F.W.247.33 | Purity: 99％ |
| Storage: | |
| Size/Unit | Price | Qty | Availability | Price Total |
|---|---|---|---|---|
| 1mg | POA | Enter qty and click checkbox |
| Catalog Number： | A11030 | CAS No.: | unlabelled: 138112-76-2 | |
| MDL: | Formula: | C15H13D4NO2 | ||
| F.W.: | 247.33 | Purity: | 99％ | |
| Package: | Unit: | mg | ||
| Appearance: | M.P.: | |||
| B.P.: | Density: | |||
| Optical Rotation: | Refractive Index: | |||
| Solubility: | Stability: | |||
| Storage: | Category: | Reference Standard | ||
| Reference: | Yous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003), | |||
| Application: | Labelled Agomelatine, a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. | |||
| Category: | Aromatics, Isotope Labelled Compounds, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals, | |||