| Catalog Number: | 
    A66009  | 
      | 
    CAS No.:  | 
    6296-53-3  | 
  
  
    | MDL:  | 
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    Formula: | 
    C10H7NO4  | 
  
  
    | F.W.:  | 
    205.17 | 
     | 
    Purity: | 
    99% | 
  
  
    | Package:    | 
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     Unit: | 
    mg | 
  
  
    | Appearance:  | 
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    M.P.: | 
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    Density: | 
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    | Optical Rotation:  | 
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    Stability: | 
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    | Storage:     | 
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    Category: | 
    Reference Standard | 
  
  
  
    | Reference:     | 
     Man, H. et al.: J. Med. Chem., 52, 1522 (2009); Nagasaka, T. et al.: J. Org. Chem., 63, 697 (1998);  | 
 
  
  
  
  
    | Application:     | 
    3-Acetylaminophthalic Anhydride is used in the synthesis of Apremilast, a potent phosphodiesterase 4 and tumor necrosis Factor-a inhibitor used in the treatment of psoriatic arthritis. Also a reagent in the preparation of Tillivalline.  | 
  
  
  
  
  
    | Category:     | 
    Aromatics, Heterocycles, Miscellaneous Reagents,  |