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Aprepitant Intermediate I

Synonyms: 5-(Chloromethyl)-1,2-dihydro-3H-1,2,4-triazol-3-one; 5-(Chloromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one; 5-Chloromethyl-2,3-dihydro-4H-1,2,4-triazol-3-one; 3-Chloromethyl-1,2,4-triazolin-5-one;
Cat. No.: A66253 CAS No.: 252742-72-6
MDL.: Formula: C3H4ClN3O
F.W.133.54 Purity: 99%
Storage:
 
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Catalog Number: A66253   CAS No.: 252742-72-6
MDL: Formula: C3H4ClN3O
F.W.: 133.54 Purity: 99%
Package: Unit: g
Appearance: M.P.:
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: Stability:
Storage: Category: Reference Standard
Reference: Wan, W. L., et al.: Chinese Chem. Lett., 24 (12), 118 (2013);
Application: 5-Chloromethyl-2H-1,2,4-triazolin-3-one, is an intermediate used in the synthesis of Aprepitant (A729800) and Fosaprepitant, used as antiemetic drugs.
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals