Aprepitant Intermediate I | 
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| Synonyms: 5-(Chloromethyl)-1,2-dihydro-3H-1,2,4-triazol-3-one; 5-(Chloromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one; 5-Chloromethyl-2,3-dihydro-4H-1,2,4-triazol-3-one; 3-Chloromethyl-1,2,4-triazolin-5-one; | |
| Cat. No.: A66253 | CAS No.: 252742-72-6 | 
| MDL.: | Formula: C3H4ClN3O | 
| F.W.133.54 | Purity: 99% | 
| Storage: | |
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             | Catalog Number: | A66253 | CAS No.: | 252742-72-6 | |
| MDL: | Formula: | C3H4ClN3O | ||
| F.W.: | 133.54 | Purity: | 99% | |
| Package: | Unit: | g | ||
| Appearance: | M.P.: | |||
| B.P.: | Density: | |||
| Optical Rotation: | Refractive Index: | |||
| Solubility: | Stability: | |||
| Storage: | Category: | Reference Standard | ||
| Reference: | Wan, W. L., et al.: Chinese Chem. Lett., 24 (12), 118 (2013); | |||
| Application: | 5-Chloromethyl-2H-1,2,4-triazolin-3-one, is an intermediate used in the synthesis of Aprepitant (A729800) and Fosaprepitant, used as antiemetic drugs. | |||
| Category: | Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals | |||








