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O-Desethyl Sildenafil
Synonyms: 5-[2-Hydroxy-5-(4-methylpiperazinylsulphonyl)phenyl]1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyramidin-7-one; 5-[2-Hydroxy-5-[[4-(methyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one;
Cat. No.: S40022	CAS No.: 139755-91-2
MDL.:	Formula: C20H26N6O4S
F.W.446.52	Purity: 99％
Storage: Refrigerator

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Catalog Number：	S40022		CAS No.:	139755-91-2
MDL:			Formula:	C20H26N6O4S
F.W.:	446.52		Purity:	99％
Package:			Unit:	mg
Appearance:	Off-White Solid		M.P.:	279-281°C (dec.)
B.P.:			Density:
Optical Rotation:			Refractive Index:
Solubility:	Aqueous Base, DMSO (Sparingly)		Stability:
Storage:	Refrigerator		Category:	Reference Standard
Reference:	Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996); Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998)
Application:	A metabolite of Sildenafil, an orally active selective type 5 cGMP phosphodiesterase inhibitor.Desethyl Gendenafil could be a possible metabolite of Gendenafil based on the metabolic pathway of Sildenafil ( Citrate salt), an analogue of Gendenafil.
Category:	Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds

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