Zonisamide |
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Synonyms: 1,2-Benzisoxazole-3-methanesulfonamide; 3-(Sulfamoylmethyl)-1,2-benzisoxazole; AD 810; Aleviatin; | |
Cat. No.: Z78000 | CAS No.: 68291-97-4/68291-98-5(Sodium Salt) |
MDL.: | Formula: C8H8N2O3S |
F.W.212.23 | Purity: 99% |
Storage: Refrigerator | |
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Catalog Number: | Z78000 | CAS No.: | 68291-97-4/68291-98-5(Sodium Salt) | |
MDL: | Formula: | C8H8N2O3S | ||
F.W.: | 212.23 | Purity: | 99% | |
Package: | Unit: | mg | ||
Appearance: | White to Off-White Solid | M.P.: | 160-163°C | |
B.P.: | Density: | |||
Optical Rotation: | Refractive Index: | |||
Solubility: | DMSO (Slightly), Methanol (Slightly) | Stability: | ||
Storage: | Refrigerator | Category: | Reference Standard | |
Reference: | Masuda, Y., et al.: Arzneim.-Forsch., 30, 477 (1980), Hammond, E.J., et al.: Gen. Pharmacol., 18, 303 (1987), Schmidt, D., et al.: Epilepsy Res., 15, 67 (1993), Sorkin, E.M., et al.: Drugs, 45, 760 (1993), | |||
Application: | Sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Anticonvulsant. | |||
Category: | Aromatics, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds |