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Zopiclone Intermediate I

Synonyms: 5-Chloro-2-pyridinamine; 2-Amino-5-chloro-pyridine; (5-Chloropyridin-2-yl)amine; 2-Amino-5-chloropyridine; 5-Chloro-2-aminopyridine; 5-Chloro-2-pyridinamine; 5-Chloro-2-pyridineamine; 5-Chloro-a-aminopyridine; NSC 26283; RP 26695
Cat. No.: Z78248 CAS No.: 1072-98-6
MDL.: Formula: C5H5ClN2
F.W.128.56 Purity: 99%
Storage: Refrigerator, under inert atmosphere
 
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Catalog Number: Z78248   CAS No.: 1072-98-6
MDL: Formula: C5H5ClN2
F.W.: 128.56 Purity: 99%
Package: Unit: g
Appearance: White to Off-White Solid M.P.: 135-137°C(dec.)
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: DMSO (Sparingly), Methanol (Sparingly) Stability:
Storage: Refrigerator, under inert atmosphere Category: Reference Standard
Reference: Noble, S., et al.: Drugs, 55, 277 (1998), Musch, B., et al.: Int. J. Clin. Psychopharmacol., 5, 147 (1990),
Application: 5-Chloro-2-pyridinamine is a useful synthetic intermediate. It can be used to synthesize zopiclone which is a Cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists.
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals