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Zopiclone Metabolite A-d8 Dihydrochloride

Synonyms: N-Desmethyl Zopiclone-d8 Dihydrochloride; (Piperazine-d8)-1-carboxylic Acid 6-(5-Chloro-pyridin-2-yl)-7-oxo-6,7-dihydro- 5H-pyrrolo[3,4-b]pyrazin-5yl Ester Dihydrochloride;
Cat. No.: Z78296 CAS No.: 1189719-74-1/1189805-43-3(free amine)/1216659-29-8(unlabelled)
MDL.: Formula: C16H9D8Cl3N6O3
F.W.455.75 Purity: 99%
Storage: -20°C Freezer, Under Inert Atmosphere
 
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Catalog Number: Z78296   CAS No.: 1189719-74-1/1189805-43-3(free amine)/1216659-29-8(unlabelled)
MDL: Formula: C16H9D8Cl3N6O3
F.W.: 455.75 Purity: 99%
Package: Unit: mg
Appearance: White to Off-White Solid M.P.: >187°C (dec.)
B.P.: Density:
Optical Rotation: Refractive Index:
Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly) Stability:
Storage: -20°C Freezer, Under Inert Atmosphere Category: Reference Standard
Reference: Fernandez, C., et al.: Clin. Pharmacokinet., 29, 431 (1995), Nordgren, H., et al.: Ther. Drug Monit., 24, 410 (2002),
Application: N-Desmethyl Zopiclone-d8 is a labelled metabolite of Zopiclone, which is Cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. This is a controlled substance (depressant) in the US but not in Canada. Sedative, hypnotic.
Category: Heterocycles, Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,